DecisionDx®-SCC Scientific References
DecisionDx®-SCC Clinical Evidence
Wysong A, Newman JG, Covington KR, et al. Validation of a 40-gene expression profile test to predict metastatic risk in localized high-risk cutaneous squamous cell carcinoma. J Am Acad Dermatol 2020. doi:https://doi.org/10.1016/j.jaad.2020.04.088
Ibrahim SF, Kasprzak J, Hall MA, et al. Improved cutaneous squamous cell carcinoma metastasis risk assessment, submitted.
Data on file, Castle Biosciences.
DecisionDx-SCC Clinical Impact Studies and Surveys
Farberg AS, Hall MA, Douglas L, et al. Integrating gene expression profiling into NCCN high-risk cutaneous squamous cell carcinoma management recommendations: Impact on patient management. Curr Med Res Opin 2020. doi:10.1080/03007995.2020.1763284
Litchman GH, Fitzgerald AL, Kurley SJ, et al. Impact of a prognostic 40-gene expression profiling test on clinical management decisions for high-risk cutaneous squamous cell carcinoma. Curr Med Res Opin 2020. doi:10.1080/03007995.2020.1763283
Teplitz R, Prado G, Litchman GB, Rigel DS. Impact of gene expression profile testing on the management of squamous cell carcinoma by dermatologists. J Drugs Dermatol 2019;18:980-4.
Guidelines, Criteria, and Staging Systems
National Comprehensive Cancer Network. Squamous Cell Skin Cancer, NCCN Guidelines Version 1.2020.
Likhacheva A, Awan M, Barker CA, et al. Definitive and postoperative radiation therapy for basal and squamous cell cancers of the skin: Executive summary of an American Society for Radiation Oncology clinical practice guideline. Pract Radiat Oncol 2020;10:8-20.
Alam M, Armstrong A, Baum C, et al. Guidelines of care for the management of cutaneous squamous cell carcinoma. J Am Acad Dermatol 2018;78:560-78.
Karia PS, Jambusaria-Pahlajani A, Harrington DP, et al. Evaluation of American Joint Committee on Cancer, International Union Against Cancer, and Brigham and Women’s Hospital tumor staging for cutaneous squamous cell carcinoma. J Clin Oncol 2014;32:327-34.
Connolly SM, Baker DR, Coldiron BM, et al. AAD/ACMS/ASDSA/ASMS 2012 appropriate use criteria for Mohs micrographic surgery: A report of the American Academy of Dermatology, American College of Mohs Surgery, American Society for Dermatologic Surgery Association, and the American Society for Mohs Surgery. J Am Acad Dermatol 2012;67:531-50.
Squamous Cell Carcinoma and Melanoma Information
SEER data release 2019.
Mansouri B, Housewright CD. The treatment of actinic keratoses— the rule rather than the exception. JAMA Dermatol 2017;153:1200.