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Why GEP?

NOW AVAILABLE: A More Objective and Comprehensive Diagnostic Testing Solution
for Difficult-to-Diagnose Melanocytic Lesions. LEARN MORE

GEP Testing Is Designed to Help Differentiate Benign Melanocytic Nevi From Malignant Melanomas

When a distinction cannot be made through clinical and histopathologic approaches like FISH, CGH, and SNP array, GEP testing is used to guide the accurate interpretation of melanocytic neoplasms whose histopathologic features are ambiguous or conflicting.

But unlike those methods, which rely on the detection of abnormalities in DNA structure, GEP testing measures RNA to detect a specific pattern of gene expression that occurs in most malignant melanomas but not in benign nevi. 

GEP Testing Can Help Reduce This Diagnostic Uncertainty

rna-3

DNA

DNA

FISH, CGH, SNP, NGS


Captures DNA abnormalities
Point mutations like BRAF

DNA Abnormalities in RREB1, MYC, p16.

Transcription

rna-2

RNA

RNA

Gene Expression (GEP) captures abnormalities in the function of the genes

myPath® Melanoma

DiffDx™-Melanoma

Translation

rna-1

Protein

Protein

Immunohistochemistry captures cell membrane protein expression

 

S100A PRAME

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For Information

Call: 866-788-9007

Expert Opinions in Melanoma

When Is the myPath Melanoma Test Most Helpful

On-Demand
Educational Programs

What's Next?

Product Overview

How Do You Order a
myPath Melanoma and
DiffDx-Melanoma Test?

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